Erratum to “Rat retinal ganglion cells co-express brain derived neurotrophic factor (BDNF) and its receptor TrkB” [Vision Res. 42 (2) (2002) 151–157]
نویسندگان
چکیده
Erratum to ‘‘Rat retinal ganglion cells co-express brain derived neurotrophic factor (BDNF) and its receptor TrkB” [Vision Res. 42 (2) (2002) 151–157] Elena Vecino *, David García-Crespo , Mónica García , Luis Martinez-Millán , Sansar C. Sharma , Eliseo Carrascal b Departamento de Biología Celular e Histología, Facultad de Medicina, Universidad del País Vasco, E-48940 Leioa, Vizcaya, Spain Departamento de Anatomía e Histología Humana, Facultad de Medicina, Universidad de Salamanca, E-37007 Salamanca, Spain Departamento de Neurociencias, Facultad de Medicina, Universidad del País Vasco, Leioa E-48940, Vizcaya, Spain Department of Ophthalmology, New York Medical College, Valhalla, NY 10595, USA
منابع مشابه
Rat retinal ganglion cells co-express brain derived neurotrophic factor (BDNF) and its receptor TrkB
The expression of brain derived neurotrophic factor (BDNF) and its preferred receptor (TrkB) in rat retinal ganglion cells (RGCs) have been determined in the present study. To identify RGCs retrograde labelling was performed with fluorogold (FG). Subsequently, retinas were immunostained with antibodies to BDNF and TrkB. We found that all RGCs labelled with FG express both BDNF and its preferred...
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Glaucoma is a progressive neuropathy characterized by loss of vision as a result of retinal ganglion cell (RGC) death. There are no effective neuroprotectants to treat this disorder. Brain-derived neurotrophic factor (BDNF) is well known to transiently delay RGC death in ocular hypertensive eyes. The CNS-specific leucine-rich repeat protein LINGO-1 contributes to the negative regulation to some...
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Sensory experience refines neuronal structure and functionality. The visual system has proved to be a productive model system to study this plasticity. In the neonatal retina, the dendritic arbors of a large proportion of ganglion cells are diffuse in the inner plexiform layer. With maturation, many of these arbors become monolaminated. Visual deprivation suppresses this remodeling. Little is k...
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PURPOSE Brain-derived neurotrophic factor (BDNF) has a potential neuroprotective effect on axotomized retinal ganglion cells (RGCs); however, the mechanism, in regard to intracellular signaling, of BDNF-induced neuroprotection of RGCs is largely unknown. Intracellular signaling was investigated, by using axotomized RGCs and the relative contribution of the two major downstream signaling routes ...
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BDNF signaling through its TrkB receptor plays a pivotal role in activity-dependent refinement of synaptic connectivity of retinal ganglion cells. Additionally, studies using TrkB knockout mice have suggested that BDNF/TrkB signaling is essential for the development of photoreceptors and for synaptic communication between photoreceptors and second order retinal neurons. Thus the action of BDNF ...
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عنوان ژورنال:
- Vision Research
دوره 50 شماره
صفحات -
تاریخ انتشار 2010